Saturday, January 25, 2020

The Economic Transformation Programme Economics Essay

The Economic Transformation Programme Economics Essay By year 2020,the government had planned that Malaysia will become a high income economy by having the Economic Transformation Program. An agency to only supervised these programmes is under the Prime Minister Department of Malaysia which are Performance Management and Delivery Unit (PEMANDU). September 21, 2010 is the launching date for this programme, it is anextensive economic transformation plan to bring Malaysias economy into high income economy. 11 Economic Transformation Program-me projects and nine under three Economic Corridors with investments totalling RM26.09bil had been announced by our beloved Prime Minister, Datuk Seri NajibTunRazak. It is expected to lift Malaysias Gross National Income (GNI) to US$523 billion by 2020, from US$6,700 to at least US$15,000 in raise per capita income, in order to be the World Banks doorstep for high income country. It is predicted that Malaysia will be able to be inline with the plan if GNI arises by 6% per annum. The 60% of the blueprints investment had been set to revitalize Malaysias private sector would, besides, from these 60 percent, 32% is from government linked companies and left with 28% more is from the government.National Key Economic Areas(NKEA) are called for various sectors for development. Figure 1.0 shows the 11 ETP projects are in seven areas which focused on oil, gas and energy, Greater Kuala Lumpur/Klang Valley, communications content and infrastructure, business services, healthcare, tourism and education. The location for the economic corridor projects are Sabah Development Corridor, Northern Corridor Economic Region as well as Iskandar Malaysia. The biggest in terms of investment is the to regenerate and revitaliseFurthermore,in the investment field,Malaysia had planned for a Greater Kuala Lumpur by remake the old township of Petaling Jaya. The plan in details are that the 40 acres (16ha) of PJ Sentral Garden City development will be a brand new green central business district of Selangor, supporting Kuala Lumpur and also cover the business hubs near by the city and state. A project also had been planned with Nusa Gapurna Development SdnBhd that is expected to produce 36,828 jobs with a GNI (gross national income) impact of RM522.97mil. Another company is GPS Tech Solutions SdnBhd which is public transportation companies and authorities will work with to roll out a web and smartphone application to provide real-time tracking of public transportation. Moreover, buses with wireless connectivity will be provided through MyPUTRAS (Malaysian Public Transportation System).It costs about RM16.29mil project. MyPUTRAS (is) a free online smart portal and smartphone application which will cater real-time tracking of buses, include time of arrival and departure which make it more convenient to all public transport users. The liberalisation of six sub-sectors under the Competition, Standards and Liberalisation strategic reform initiative. These sub-sectors are the legal services, medical specialist services, dental specialist services, international schools, private universities and telecommunications (Network Facilities Providers (NFP) and Network Services Providers (NSP) sector. Thus,it brings a total of 15 from 17 sub-sectors that were announced during the Budget 2012. Another field, engineering and architectural services, as well as quantity surveying (a new sub-sector), will be the amended legislation giving effect to the liberalisation is passed. This ETP are expected to RM10.1b boost gross national Income, in addition to 64,282 jobs created by 2020. Investment is also one of the main attraction of Malaysia due to the global uncertainty.The strong economic growth had attract many foreign investors and had seen Malaysia as a developing country. Our economists had forecasted that Malaysia will have a strong domestic consumption that keeps expanding especially on our structural changes and also the projects that had been in Economic Transformation Programe. The Performance Management and Delivery Unit (Pemandu) also believe that we also have to monitor the plan to be followed accordingly. They make a laboratory in order to know the progress of the ETP. In 2010, 131 entry point projects (EPPs) and 60 business opportunities have been identified in this laboratory in a period of 2 months by 425 people that involve in it between government and private sector .211 organizationshad taken place, which are Shell, Exxon-Mobil, MYDIN, Sime Darby, Genting Plantations, Petronas, PricewaterhouseCoopers, Celcom, Ericsson, Maybank, Tesco, Sunway Medical Centre, Masterskill University College, The Body Shop, AirAsia, Malaysia Airlines, RapidKL and Digi Telecommunications. It is approximated that these initiatives will generate RM500 billion of national income per year and create up to 2.2 million jobs by 2020. The private sector had contributed 92% ot the jobs opportunities. National Key Economic Areas Since 92% of the total investments will originate from private sector, the sector is much involved in the planning of this transformation blueprint. A workshop had been organised by Performance and Delivery Unit (PEMANDU) to identify the 12 National Key Economic Areas (NKEA). The NKEA is the key driver to the success of this program as such activities have the potential to contribute significantly to the growth of the economy of Malaysia. Besides that, there are 131 entry point projects (EPP) identified under the NKEA, which includes a high speed railway connecting Penang to Singapore and MRT in Kuala Lumpur. Economic activities that are categorized as NKRA will be prioritized in government planning and funds allocation. Policies will be amended to facilitate fast track implementation of such activities, including liberalizing the market and removal of bottlenecks. With this policy, private companies are invited to get involved, with PEMANDU pushing for the implementation to speed up the implementation. Among the companies that are involved in the transformation programme are YTL, Shell Malaysia, Airasia, HovidInc, Select-TV, Exxon-Mobil, Dialog Group, TenagaNasional, Cisco. As an example, in oil, gas, and energy sector, that is the strength of Malaysias economic growth. As of 2010 the energy sector has been an essential part of Malaysias economic growth and it contributes 20 percent of GDP. Another strength is the palm oil industry.As of 2010 ,the fourth largest component of the national economy is belong to Malaysia and contribute to RM53 billion of gross national income. The industry cater the value chain from plantations to processing. The development of this industry is largely for private and remains heavily oriented towards plantations. With the contraints in land available to continue the evolution of plantations, the government craving to boostcompetency in production and focus on adapting great value through downstream activities. The Palm Oil NKEA is purposely forgiving high impact in total contributions to national income from the palm oil industry by RM125 billion to forecasted RM178 billion by 2020. The government aims that 41,000 new jobs will be created in this field. Palm oil related EPPs which focused more on upstream productivity and downstream expansion. These EPPs will focus on replanting of aging oil palms, mechanising plantations, stringently enforcing best practices to enhance yields, implementing strict quality control to enhance oil extraction, and developing biogas facilities at palm mills to capture the methane released during milling. Downstream expansion and sustainability will be achieved by capturing the lucrative market segments that focus more on refined products such as oleo-derivatives, food, health products, and bio-fules. These projects are believed will require funding of RM124 billion over the next 10 years with 98 percent of the funding coming from the private sector as being said by the government. The government has given renewed focus to Malaysias international economic relations, including liberalization and increasing interaction with the global economy. This approach is understandable for a small, open economy that is particularly  dependent on export-driven growth, and faces considerable pressure to attract FDI and increase its exports. Malaysia no longer takes a rigid, narrow stance in choosing its economic partners having decided not to confine itself to one particular global orientation, be it east or west and is signatory to several FTAs through ASEAN. These include FTAs that ASEAN concluded with China, India, Australia, New Zealand, Japan and Korea. Beyond this, Malaysia has also entered into bilateral agreements with Japan, India, New Zealand and Pakistan. Reform in other areas will be equally essential. Government procurement, intellectual property rights and the opening of the domestic financial market (as well as other services) will each have to be addressed. Hopefully, the government will also be nudged into fulfilling the states traditional role of providing citizens with greater access to education, health care, housing and a good public transportation system. First, the attempt to forge links with economies as diverse as China, Pakistan and Chile can be criticised for lacking focus. A slower rate of global engagement might have been preferable, but the international race to conclude FTAs would have excluded Malaysia, had this strategy not been pursued. The government wanted to seize the opportunity to cast its net wider for overseas markets, and the 2008 crisis pushed Malaysia to explore such opportunities. In effect, Malaysia may be seeking membership in a multiplicity of arrangements without any overarching strategy. But to define the objective of entering into an FTA as solely to secure more markets is naÃÆ' ¯ve. Second, the government has given a special priority to developing links with Islamic economies. The Developing 8 Preferential Agreement (with eight developing Islamic countries) and the Trade Preferential System among the Organisation of the Islamic Conference countries are two particularly relevant agreements that Malaysia has ratified in this regard. Sidelining economic relations with Islamic economies, even when the rationale is questionable, can evoke sensitivities among certain quarters of the policy community, but Najib has deftly sidestepped these issues and has forged ties as much with Pakistan  as with China. It would, of course, be hugely myopic to ignore China or India in Malaysias international economic relations. The government strategy for global economic engagement has been criticised on several grounds, and as negotiations for the TPP and the EU-Malaysia FTA progress, opposition could mount. Nevertheless, early successes will put Malaysia in good stead to pursue a dual approach of increasing interactions with the global economy while implementing strong domestic reforms. Fiscal Policy in Malaysia Malaysia follows an explicit fiscal policy rule that disallows an operating deficit in any given year. This aims at making a credible commitment to long term fiscal sustainability by applying discipline to annual budgets. As mentioned before in this report, the implementation of Economic Transformation Plan to move towards high income has proven to be vertically taken off with most targets has been achieved and exceeded within the span of more than 2 years. Based on the executive report by bank Negara Malaysia (BNM), Malaysia is moving from a resource based economy into more service centric economy as most of high-income nations globally. Fiscal policy can be further explained as the use of government spending and taxation to further influenced the economy. It is typically to promote a sustainable growth of economy in the long run as well as stabilizing the macroeconomic post crisis such as expanding spending, tax cutting to further stimulate a recovering economy. In the longer term, the government can foster a sustainable economy by improving infrastructures, providing better education and scholarship to boost the professional participation among the public, encourage public participation in corporate as well as academic. In the short term the fall in exports was offset by an unprecedented fiscal stimulus programme launched over two rounds started in 2008. In the total governments countercyclical measures amounted to an estimated RM67, 000,000,000, which were allocated to support private enterprise. The second package which was announced on March 2009, set aside RM 5,000,000,000 to support firms that need access to working capital, with specific involvement in tourism, aviation and auto industries. As such, Malaysia is sought to speed up the implementation of existing infrastructure projects such as the extended rail of Light Railway Transit (LRT), Mass Rapid Transit (MRT), targeting in particular the expansion of high speed broadband network, and also airport upgrades. Although Malaysia has relatively low debt to GDP ratio of around 50%, the global issue of sovereign debt with Greece in early 2010 is likely to put pressure on Malaysia to introduce fiscal tightening measures to prevent increased lending cost. The fiscal deficit target for 2010 has been revised to 5.3% taking into consideration RM12,000,000,000 supplementary budget and the revised 2010 GDP. The 2009 budget gap reached 7% of GDP, largely due to fiscal stimulus plan. The level of government expenditure is forecasted to decline faster with the government promising to introduce an efficiency drive and reduce the subsidies on fuel, food and education. This measure would help to reduce the structural and fiscal deficit, ensuring the governments consolidation efforts have a permanent impact. The spending target set for 2010 is RM 201,700,000,000 in 2010 and the fiscal deficit is expected to decline to 5.3%. Formulation of Fiscal Rules Basically there are 3 major types of fiscal policy rules. First is the balanced-budget or deficit rules comprises of 3 balance between the overall revenue and expenditure; or limit on government deficit as proportion of GDP. Another one is balance between structural and expenditure, and balance between current revenue and current expenditure. The second type of fiscal policy rules is the borrowing rules which prohibits on government borrowing from domestic sources as well as prohibits government borrowing from central bank; or limit on such borrowing as a proportion of past government revenue or expenditure. The third and last fiscal rule is debt or reserve rules which limits on stock of gross government liabilities as a proportion of GDP and target stock of reserves of extrabudgetay contingency funds (such as social security fund) a a proportion of annual benefit payments. In achieving a strong commitment to fiscal sustainability as well as in ensuring the sustainable long term growth, Malaysia is facing implementation constraint; however there is need to adjust the existing procedure to result in enhancing its efficiency. Flexibility can be incorporated into fiscal rules by expanding the horizon for budget formulation including the application of fiscal rules; to cover the course of a business cycle would provide the economy with improved shock-absorptive capacity. For instance, the rule on the annual operating budget for Malaysia could be modified from one year to allow an operating deficit during an economic downturn while observing the balance over the course of a business cycle. It often takes awhile to implement the spending measures, and may be in effect even longer than needed. This would require a medium-term fiscal framework for planning and forecasting. Second, the government can introduce contingency measures during the budget process. It can be either to add stimulus or withdraw as it required. This could include the elimination of a surtax and introduction of a stabilization fund. Although a cut increase in capital spending is effective, but it should be used only as a last resort. This can be triggered during budget execution if actual budge performance deviates significantly from the planned path. Similarly, the scope of stabilizers can be improvised by a more progressive tax system. For instance, tax on high-income household at a higher rate than off the lower income household. There are two types of taxes that can be imposed which are levied to transfer fund from private to public use namely direct taxes levied from income, profit and wealth as well as indirect taxes such as excise duty, sales taxes, quit rent and so on.

Friday, January 17, 2020

A Review of the Role of Soluble Fiber in Health with Specific Reference to Wheat Dextrin

Journal of International Medical Research http://imr. sagepub. com/ A Review of the Role of Soluble Fiber in Health with Specific Reference to Wheat Dextrin JL Slavin, V Savarino, A Paredes-Diaz and G Fotopoulos Journal of International Medical Research 2009 37: 1 DOI: 10. 1177/147323000903700101 The online version of this article can be found at: http://imr. sagepub. com/content/37/1/1 Published by: http://www. sagepublications. com Additional services and information for Journal of International Medical Research can be found at: Email Alerts: http://imr. agepub. com/cgi/alerts Subscriptions: http://imr. sagepub. com/subscriptions Reprints: http://www. sagepub. com/journalsReprints. nav Permissions: http://www. sagepub. com/journalsPermissions. nav >> Version of Record – Feb 1, 2009 What is This? Downloaded from imr. sagepub. com by guest on March 27, 2013 The Journal of International Medical Research 2009; 37: 1 – 17 A Review of the Role of Soluble Fiber in Health wit h Specific Reference to Wheat Dextrin JL SLAVIN1, V SAVARINO2, A PAREDES-DIAZ3* 1 AND G FOTOPOULOS4Department of Food Science and Nutrition, University of Minnesota, St Paul, Minnesota, USA; 2 Department of Internal Medicine, Gastroenterology Unit, Genoa, Italy; 3Novartis Consumer Health, Parsippany, New Jersey, USA; 4Novartis Consumer Health, Nyon, Switzerland dextrin, based on a search of PubMed. The evidence suggests that soluble fibers help to regulate the digestive system, may increase micronutrient absorption, stabilize blood glucose and lower serum lipids, may prevent several gastrointestinal disorders, and have an accepted role in the prevention of cardiovascular disease.It is concluded that supplementation with soluble fibers (e. g. wheat dextrin) may be useful in individuals at risk of a lower than recommended dietary fiber intake. ACIDS; Dietary fiber is widely recognized to have a beneficial role in overall health, but only at adequate levels (25 – 38 g/day for he althy adults). Wheat dextrin in particular is a soluble fiber that can easily be added to the diet and is widely used in the food industry. There is some debate about whether increased intake of soluble fibers leads to health benefits.This paper reviews the evidence regarding the physiological effects and potential health benefits of the addition of soluble dietary fibers, with specific reference to wheat KEY WORDS: SOLUBLE FIBER; WHEAT DEXTRIN; SHORT-CHAIN FATTY PHYSIOLOGICAL EFFECTS; HEALTH BENEFITS PREBIOTICS; Introduction Fiber, the indigestible part of plants such as cereals, fruits and vegetables (Table 1), has a fundamental role in the regulation of the digestive system and may help to prevent troublesome disorders such as constipation,1 – 3 diarrhea4 – 6 and irritable bowel syndrome. – 9 Fiber may also help to regulate the absorption of micronutrients,3,10,11 stabilize glucose12 – 14 and cholesterol levels,15 – 17 have a role in cardiovascu lar health18 – 20 and possibly help to prevent some forms of cancer. 21 – 23 *Current address: 90 Possum Way, New Providence, NJ 07974, USA. Many nutrition and healthcare professionals use the terms ‘soluble’ and ‘insoluble’ fibers for nutrition labeling. 24 – 27 Soluble fibers dissolve in water and usually form a gel.They are generally fermented by bacteria in the lower intestine, but they are indigestible and hence not absorbed into the bloodstream. 24,28 Soluble fibers also ferment to form short-chain fatty acids (SCFAs) such as butyrate, acetate and propionate (Table 2). 17,29 – 34 Short-chain fatty acids generate approximately 1 – 2 kcal/g of ingested fiber, so are used as an energy source by the intestinal Downloaded from imr. sagepub. com by guest on March 27, 2013 1 JL Slavin, V Savarino, A Paredes-Diaz et al.The health benefits of soluble fiber TABLE 1: Classification systems for fiber based on four different fibe r characteristics Dietary fibers Lignin (polyphenolic compound, in cell walls of woody plants and seeds) Cellulose (glucose polymer, in all plant cell walls) ? -Glucans (glucose polymers, in oats, barley) Hemicelluloses (polysaccharides, in plant cell walls) Pectins (viscous polysaccharides, in fruits and berries) Gums (viscous polysaccharides, in seeds; e. g. uar gum) Inulin and oligofructose (mixture of fructose chains, in plants such as onions) Resistant starch (starch in plant cell walls; inaccessible to human digestive enzymes; often found in bananas and legumes; may also be formed by food processing) Soluble fibers Wheat dextrin ? -Glucans Gums (e. g. guar gum, partially hydrolyzed guar gum) Mucilages (e. g. psyllium) Pectins Fructo-oligosaccharides Some hemicelluloses Sources: oat products, legumes (dry beans, peas, lentils) Fermentable fibers Wheat dextrin Pectins ? Glucans Guar gum Partially hydrolyzed guar gum Inulin and oligofructose Sources: oats, barley, fruits, vegetab les Viscous fibers Pectins ? -Glucans Some gums (e. g. guar gum) Mucilages (e. g. psyllium) Functional fibers Resistant dextrins (e. g. wheat dextrin) (indigestible polysaccharides formed when starch is heated and treated with enzymes; includes resistant maltodextrins) Psyllium (viscous mucilage, isolated from husks of psyllium seeds; also known as ispaghula husk) Chitin and chitosan (nondigestible carbohydrate from exoskeletons of crustaceans, e. . crabs, lobsters; deacetylation of chitin gives chitosan, a nondigestible glucosamine polymer) Fructo-oligosaccharides (FOS, short synthetic fructose) Polydextrose and polyols (synthetic polysaccharides used as bulking agents and sugar substitutes in foods) Insoluble fibers Cellulose Lignin Some pectins Some hemicelluloses Sources: wheat bran, some vegetables Non-fermentable fibers Cellulose Lignin Sources: cereal fibers rich in cellulose (e. g. wheat bran)Non-viscous fibers Cellulose Lignin Some hemicelluloses mucosa and are absorbed thr ough the colonic wall, where they are metabolized to produce energy or transported into the general circulation. 29 SCFAs also stimulate epithelial cell differentiation and proliferation. 29 Soluble fibers can also promote the growth of colonic Downloaded from imr. sagepub. com by guest on March 27, 2013 2 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiberTABLE 2: Short-chain fatty acids (SCFA) produced by fermentable, soluble fiber17,29 – 34 Butyrate Widely recognized as the most significant acid in terms of its documented effects in the colon The preferred nutrient for the cells lining the colonic epithelium, in particular the distal colon and rectum The preferred substrate for colonocytes Positive effects on colonic mucosal growth, crypt cell proliferation, and early-response gene expression Acetate A fuel for skeletal and cardiac muscle, kidney and the brain A substrate for fatty acid and cholesterol synthesis Propionate Metabolized by the l iver Only SCFA that can be a major source of glucose (after metabolism, used for energy production) May play a role in cholesterol lowering bacterial flora (prebiotic effect). 35 – 37 Insoluble fibers, on the other and, do not dissolve in water, are generally less fermentable by colonic microflora and are indigestible,26 so pass through the intestines almost intact. Insoluble fibers have passive water-attracting properties that help to normalize large bowel function by acting like a sponge, pulling water into the stool and making it easier to pass. 38 They may also decelerate intestinal transit time, increase fecal weight through bulk action, delay glucose absorption and help to control and balance the pH in the intestines. 39,40 In the USA, the daily intake recommended by the American Dietetic Association (ADA) is 20 – 35 g fiber/day for healthy adults, and ‘age plus 5 g/day’ for children. 6 The World Health Organization (WHO) recommends > 25 g/day,41 whi le the British Nutrition Foundation recommends 12 – 24 g/day for healthy adults. 42 The Food and Nutrition Board of the Institute of Medicine established the Adequate Intake (AI) recommendation for fiber (both soluble and insoluble),24 which ranges from 19 to 38 g/day for children, depending on age, and from 25 to 38 g/day for healthy adults. The majority of people, however, do not seem to achieve the recommended daily intake of fiber, and women in general seem to consume lower amounts than men. 43,44 Wheat dextrin is a soluble fiber that has been widely used in the food industry because it has a low viscosity and so has a good consistency when added to water, beverages or soft food. 4 It is formed by heating wheat starch at high temperature, followed by enzymatic (amylase) treatment to form a resistant starch. 24,45 It qualifies as a dietary fiber because the non-digestible glucoside linkages (Fig. 1) lead to incomplete hydrolysation, so that only a small percentage of wheat dextrin is absorbed in the small intestine and the rest is slowly fermented in the large intestine. 3 This review aims to assess the evidence regarding the physiological effects and potential health benefits of supplementing the diet with soluble fibers, with specific reference to wheat dextrin. Data source The PubMed database (US National Library Downloaded from imr. sagepub. om by guest on March 27, 2013 3 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiber CH2OH O OH O OH O CH2OH O OH HO O CH2 O OH O OH O OH CH2OH O OH O OH CH2OH O OH OH O OH OH O OH O OH HO 1:2 bond O O CH2OH O OH CH2OH O O OH OH O OH 1:3 bond CH2OH O OH O CH2 O OH O HO CH2OH O OH 1:6 bond O CH2 O H2 C O O CH2OH O CH2OH O OH O HO OH FIGURE 1: Chemical structure of wheat dextrin of Medicine, National Institutes of Health, Bethesda, MD, USA) was searched (to July 2007) using the terms ‘wheat dextrin’ and ‘soluble fiber’, and studies were selected based on wh ether they evaluated the physiological or clinical effects of soluble fibers.Although this non-systematic approach limits the review in that a quantitative analysis was not performed, it does allow a general and potentially useful overview of the effects of supplementation with soluble fibers. Physiological effects of soluble fibers FERMENTABILITY In vitro fermentation of wheat dextrin, inulin and partially hydrolysed guar gum (PHGG), and analysis of the resulting SCFA production over a 24-h period17 revealed that all three fibers demonstrated detectable fermentability. Acetate was the main SCFA produced by all fibers, accounting for about 50% of the total SCFA. Over 24 h, wheat dextrin produced substantially more total SCFA, propionate and butyrate than PHGG, which consistently showed lower fermentability at all time points (Fig. 2A – 2C).To reduce gas production (which can be socially undesirable and cause uncomfortable bloating), extensive fermentation at 24 h is desirable , while fast fermentation (e. g. high values at 4 h) may be undesirable. The total amount of SCFA produced by wheat dextrin at 4 h was just over half the amount produced by glucose Downloaded from imr. sagepub. com by guest on March 27, 2013 4 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiber A Concentration ( µmol/ml) 120 100 80 60 40 20 0 B Concentration ( µmol/ml) 16 14 12 10 8 6 4 2 0 0 4 8 12 Time since start of fermentation (h) 24 0 4 8 12 Time since start of fermentation (h) 24 C Concentration ( µmol/ml) 45 40 35 30 25 20 15 10 5 0 0 4 8 12 Time since start of fermentation (h) 24 Wheat dextrin PHGG Inulin F97 GlucoseFIGURE 2: Analysis of short-chain fatty acid (SCFA) production following in vitro fermentation of wheat dextrin, partially hydrolysed guar gum (PHGG) inulin and glucose (positive control) over 24 h: (A) total SCFA production; (B) butyrate production; and (C) propionate production17 (positive control) and almost half the amount produced by inulin at the same time point (Fig. 2A). The fermentation of wheat dextrin, therefore, occurred slowly over 24 h, so its consumption was less likely to result in the gas production that can occur as a result of rapid fiber fermentation. composition towards a more beneficial distribution. 17,46 For example, the consumption of fructo-oligosaccharides led to an increase in fecal bifidobacteria,36,47,48 while ingestion of polydextrose resulted in a dosedependent decrease in bacteriodes and an increase in beneficial lactobacilli and bifidobacteria. 49 Administration of PHGG for 3 weeks increased the Lactobacillus spp count in feces. 0 Consumption of wheat dextrin led to a lower colonic pH, an increase in the fecal concentration of glucosidases, a statistically significant increase in the beneficial lactobacilli population and a statistically significant decrease in pathogenic Clostridium perfringens. 35 In another study, wheat dextrin increased the fecal concentration of glu cosidase;45,51 increased glucosidase activity is considered beneficial to the host and is linked to substrate fermentation leading to more SCFAs and lactic acid production. PREBIOTIC EFFECT The SCFAs produced by soluble fermentable fibers are moderately strong acids (pK 4. 8)29 and so they lower colonic pH. Lowering the pH in the large ntestine may support the growth of bifidobacteria and lactobacilli because they have a strong intrinsic resistance to acid and the lower pH may help to prevent the growth of pH-sensitive pathogenic bacteria such as clostridia. 30 Many soluble fermentable fibers have demonstrated a significant prebiotic effect and alter the intestinal microflora Downloaded from imr. sagepub. com by guest on March 27, 2013 5 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiber EFFECT ON LAXATION AND REGULARITY The formation of SCFAs helps to improve laxation and regularity by increasing fecal bulk and weight and increasing the waterholding c apacity (and thus the hydration) of feces. 0,46 The increase in fecal bulk and weight results from the presence of fiber, the water that the fiber holds and the partial fermentation of the fiber, which increases the amount of bacteria in the feces. 52 Studies have confirmed that consumption of the soluble fibers inulin or oligofructose result in an increase in fecal weight,53 while inulin helped to reduce constipation2 and polydextrose increased fecal mass and sometimes stool frequency. 49,54 Consumption of psyllium significantly increased stool frequency and stool weight, increased stool water content, improved stool consistency, increased the frequency of bowel movements and reduced pain on defecation. 55 – 59 Wheat dextrin significantly increased dry fecal output by 70% (P < 0. 02) and wet fecal output by 45% (P < 0. 05) (Fig. 3). The increase in wet fecal output was due to increased dry matter output (38%) and increased water output (62%). IMPROVED NUTRIENT/MINERAL ABSORP TION Although dietary fibers are traditionally thought to decrease mineral absorption, animal models and human studies have demonstrated that soluble fermentable fibers appear to increase the absorption of certain minerals. 3,10,60 – 62 For example, soluble fibers may increase calcium absorption through the increased production of SCFAs, with an increase in the villus crypt height, number of epithelial cells per crypt, cecal vein flow and mucosal-to-serosal calcium fluxes and stimulation of the expression of calbindinD9K, thereby enhancing the active calcium transport route. 3 Soluble fibers may also increase the absorption of other minerals such as magnesium, zinc and iron. 3,10,11 Studies in rats showed that the absorption of calcium, magnesium and/or zinc may be enhanced by guar gum,64 inulin,10,65 oligofructose65 and PHGG. 11 In healthy men supplemented with either wheat dextrin or dextrose (100 g/day), ingestion of wheat dextrin significantly increased magnesium apparent absorption (50. 9%, P = 0. 001) and retention (30. 9 mg/day, P = 0. 024) and tended 80 P < 0. 02 70 60 Increase (%) 50 40 30 20 10 0 Wet fecal output FIGURE 3: Effect of wheat dextrin on fecal output3 Dry fecal output P < 0. 05 45% 70% Downloaded from imr. sagepub. om by guest on March 27, 2013 6 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiber (not statistically significant) to increase calcium apparent absorption (37. 4%) and retention (111 mg/day) (Table 3). 3 prandial plasma glucose concentrations (–13 mg, P = 0. 04) and a significant reduction in the urinary excretion of glucose (P = 0. 008) compared with the low-fiber diet. 13 In fact, the effects of fiber on glucose concentrations are most evident in individuals with diabetes mellitus and it has been suggested that diabetics should consume 25 – 50 g/day of dietary fiber, with ? 55% of their calorie intake coming from carbohydrate. 4 To assess the effect of fiber on the risk for diabetes, more than 65 000 women (40 – 65 years of age) were followed for 6 years; it was found that dietary glycemic index and glycemic load were positively associated with the development of type 2 diabetes, and dietary fiber was inversely associated. 75 Beyond the effects of fiber on post-prandial glucose and insulin, fiber alters the responses and actions of the gut hormones gastric inhibitory peptide,76 glucagon-like peptide177 and cholecystokinin (CCK). 78 CCK is a peptide hormone and neurotransmitter that regulates gut motility, gall bladder contraction and pancreatic enzyme secretion and may mediate the post-prandial glycemic and insulinemic response to viscous fibers. A direct correlation has been reported between post-prandial CCK and subjective satiety scores following ingestion of foods with varying amounts of fiber. 79,80 DECREASED GLYCEMIA AND INSULINEMIAThrough the production of SCFAs, soluble fibers can stimulate pancreatic insulin release and affect liver con trol of glycogen breakdown,66,67 and so may be effective in decreasing blood glucose and insulin levels and improving glycemic and insulinemic indices. 68 Guar gum,69,70 inulin12 and dextrin71 were all found to improve postprandial glycemia. In healthy subjects, the glycemic index of wheat dextrin was 25% compared with dextrose and the insulin response with wheat dextrin was also low at 13% compared with dextrose. 14 Resistant dextrins led to reduced blood glucose concentrations and insulin secretion in rats after sucrose or maltose loading,72,73 reduced the post-prandial blood glucose concentrations in healthy men and women,13 and significantly reduced fasting blood glucose concentrations in type 2 diabetics. 6 In patients with type 2 diabetes given a diet high (25 g soluble plus 25 g insoluble fiber) or low (8 g soluble plus 16 g insoluble fiber) in total fiber, the high-fiber diet resulted in significantly lower pre- TABLE 3: Effect of wheat dextrin supplementation (100 g/day) on the absorption and retention of magnesium and calcium in healthy men3 Dextrose diet Calcium Apparent absorption, mean, mg/day (%) Retention, mean, mg/day Magnesium Apparent absorption, mean, mg/day (%) Retention, mean, mg/day 187 (28. 8) 39. 3 65 (30. 4) –0. 3 Wheat dextrin diet 269 (37. 4) 111 117 (50. 9) 30. 9 Statistical significance (P-value) 0. 093 0. 122 0. 001 0. 024 Downloaded from imr. sagepub. com by guest on March 27, 2013 7 JL Slavin, V Savarino, A Paredes-Diaz et al.The health benefits of soluble fiber REDUCED CHOLESTEROL LEVELS The SFCAs can suppress cholesterol synthesis by the liver and may reduce serum levels of low-density lipoprotein cholesterol (LDL-C) and triglycerides. 81 Soluble, viscous fibers are also thought to exert their hypocholesterolemic action by increasing fecal sterol excretion and stimulating hepatic bile acid synthesis. 82,83 In a metaanalysis of 67 controlled trials, consumption of 2 – 10 g/day of fiber (i. e. pectin, oat bran, gua r gum, psyllium) reduced total cholesterol by 4% and LDL-C by 7% compared with placebo. 15 No significant effect was observed on serum high-density lipoprotein cholesterol (HDL-C) and triacylglycerol concentrations.A greater reduction in serum total cholesterol and triacylglycerol concentrations was also noted in type 2 diabetics who consumed 60 g/day resistant dextrin compared with type 2 diabetics or healthy adults who consumed 30 g/day. 16 No difference was observed in the concentration of HDL-C. A diet high in total fiber (25 g soluble plus 25 g insoluble fiber) led to significantly reduced plasma total cholesterol (P = 0. 02), very-low-density lipoprotein cholesterol (VLDL-C) (P = 0. 01) and triglyceride (P = 0. 02) concentrations compared with a low-fiber diet, indicating that high fiber intake, especially soluble fiber, improves plasma lipid profile. 3 It has also been proposed that soluble fermentable fibers may lead to a reduction of cholesterol levels via the increased amo unts of propionate produced during their fermentation by the commensal bacteria, because propionate may inhibit cholesterol biosynthesis. 84 Fibers producing high amounts of SCFAs (particularly propionate), such as wheat dextrin, may help to sustain cholesterol levels within the normal range. 17 The cholesterol-lowering effects of wheat dextrin have been demonstrated in animal trials. 85 The findings suggest that its cholesterol-lowering effect is likely to be related to reduced cholesterol and bile salt absorption. However, not all soluble fibers are hypocholesterolemic agents; for example, oat bran has been shown to lower serum lipids while wheat bran did not. 81 IMMUNE FUNCTIONIt is possible that SCFAs help to improve immune function, as they stimulate the production of T helper cells, antibodies, leukocytes and splenocyte cytokines, all of which have a crucial role in immune protection. 86,87 In addition, SCFAs improve the barrier properties of the colonic mucosal layer, thus in hibiting inflammatory and adhesion irritants. 88 – 90 Lactic-acid-forming bacteria competitively inhibit and/or suppress the growth of pathogenic bacteria, and may have a positive influence on immune function. 91,92 WEIGHT REDUCTION Obesity is associated with increased energy intake and decreased consumption of fiberrich foods,93 while fiber intake is inversely associated with body weight and body fat. 94 – 97 Increasing daily fiber intake is an effective way of providing a satiating effect. 8 Dietary fiber also decreases gastric emptying and/or slows energy and nutrient absorption (a fiber-rich meal, which is also usually richer in micronutrients, is processed more slowly and nutrient absorption occurs over a greater period of time99), leading to lower post-prandial glucose and lipid levels. Furthermore, addition of dietary fiber to a low-calorie diet has been shown to lead to a significantly greater weight loss (8. 0 kg) compared with placebo (5. 8 kg). 100 When post -menopausal women consumed higher fiber diets, this was associated with significant weight loss. 101 A high Downloaded from imr. sagepub. com by guest on March 27, 2013 8 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiber carbohydrate diet consumed ad libitum (i. e. elf-regulating), without energy restriction or change in energy intake, caused significant body weight and body fat losses in older men and women, with a significant decrease in thigh fat area (P = 0. 003). 102 A review of the effects of increased fiber (high-fiber foods or supplementation) on hunger, satiety, energy intake and body weight revealed that controlled energy intake with increased dietary fiber led to an increase in post-meal satiety and a decrease in subsequent hunger. 103 With ad libitum energy intake, increased dietary fiber (14 g/day) resulted in an average 10% decrease in energy intake and 1. 9 kg weight loss over 3. 8 months of intervention. The effects of increasing dieta ry fiber were reported to be greater in obese individuals.When evaluating the effects of 1 week of supplementation with soluble fiber (guar gum, 40 g/day) on hunger, satiety rating and energy intake, mean daily energy intake decreased significantly from 6. 7 to 5. 4 MJ, while hunger and satiety scores did not change. 104 Long-term (4 – 5 weeks) assessment of wheat dextrin (30 or 45 g/day) supplementation demonstrated a trend towards better weight maintenance; compared with baseline, body weight was increased in the control group supplemented with pure absorbable maltodextrin (+0. 87 kg; P = 0. 07), whereas body weight remained stable in the wheat dextrin-treated groups (+0. 0 kg). 35 sometimes stool frequency. 9,54 Psyllium significantly increased stool frequency and stool weight, increased stool water content, improved stool consistency, increased the frequency of bowel movements and reduced pain on defecation. 55 – 59 Administration of PHGG for 3 weeks increased the frequency of defecation (+0. 17 /day), increased fecal moisture (+5%) and decreased fecal pH. 50 Supplementation with PHGG also helped to reduce the use of laxatives (from an average of 2. 0 to 0. 2 doses/day). 105 Wheat dextrin (100 g/day) had a positive effect on fecal output in healthy men,3 with an average 45% increase in wet fecal weight (P < 0. 05) and 70% increase in dry fecal output (P < 0. 02) (Fig. 3). DIARRHEA Increased intake of soluble fiber may enhance recovery and improve stool consistency in diarrhea. ,5,106 – 109 Persistent diarrhea resolved in more children taking PHGG (84%) compared with those on the control diet (62%) (odds ratio 3. 12), while the duration of diarrhea was reduced and there was a trend towards reduction in daily stool weight that reached significance on days 4 – 7. 6 Compared with non-fiber control in children, PHGG significantly reduced the mean frequency of diarrhea (8. 8% versus 32. 0%; P = 0. 001), resulted in significantly fewer days with diarrhea per total feeding days (10. 8% versus 31. 5%; P < 0. 001) and led to a significantly lower mean diarrhea score (4. 8 versus 9. 4; P < 0. 001). 110 PHGG also suppressed diarrhea caused by the ingestion of high levels of non-digestible sugar substitutes. 11 In elderly patients with diarrhea, 4-week supplementation with soluble dietary fiber (7 g/day) significantly reduced the water content of feces (P < 0. 01), the fecal pH (P < 0. 05) and the frequency of daily bowel movements (P < 0. 05). 5 In addition, the fecal characteristics improved The role of soluble fiber in disease CONSTIPATION Increased daily fiber intake can ameliorate constipation. 40,49,52 – 59 Consumption of inulin or oligofructose was shown to increase fecal weight,53 inulin reduced constipation2 and polydextrose increased fecal mass and Downloaded from imr. sagepub. com by guest on March 27, 2013 9 JL Slavin, V Savarino, A Paredes-Diaz et al.The health benefits of soluble fiber and the tota l level of SCFAs increased significantly (P < 0. 05). 5 In patients with fecal incontinence, significantly fewer incontinent stools were observed in those who consumed dietary fiber (psyllium or gum arabic) than those receiving placebo. 4 Improvements in fecal incontinence or stool consistency did not appear to be related to unfermented dietary fiber. However, the effects of increased soluble fiber on diarrhea are inconclusive, as a meta-analysis of randomized, controlled trials found no evidence that dietary fiber was effective in treating diarrhea. 112 randomized studies would be useful to confirm the potentially beneficial effects of soluble fiber in IBS.DIVERTICULOSIS A diet low in fiber is thought to play a role in the pathogenesis of diverticular disease. 114 Increasing dietary fiber produces bulky, soft stools, facilitating defecation and reducing intracolonic pressure. 114 Increased fiber also helps to promote regular bowel function and is important in controlling and minimi zing diverticular disease. 115 – 117 Non-viscous soluble fiber is associated with a decreased risk of diverticular disease and an improvement of bowel pain. 115 In patients with diverticulosis, it is recommended that patients consume 20 – 35 g/day of fiber either through the diet or supplementation. 118 IRRITABLE BOWEL SYNDROMETreatment for irritable bowel syndrome (IBS) is aimed at alleviating symptoms. In patients with mild symptoms, fiber supplementation (particularly non-gelling soluble fibers) may help to relieve the severity and frequency of IBS symptoms, including abdominal pain, spasms or distension/tension, bowel dysfunction (e. g. fluctuation between constipation and diarrhea) and flatulence. 8,9,113 PHGG was better tolerated than wheat bran and more readily accepted by IBS patients, resulting in an improved quality of life during the treatment period. 113 PHGG also had a positive effect on evacuation frequency with a decrease in the frequency of IBS symptoms such as flatulence, abdominal tension and abdominal spasm. 13 Based on its physiological properties, wheat dextrin may also help to alleviate gastrointestinal symptoms associated with IBS through increased fecal output,3 enhanced prebiotic capabilities35,45 and significant but slow fermentation in the lower intestine, producing high concentrations of SCFAs but lower amounts of gas, which could be an important aspect in relieving the discomfort caused by IBS. 17 However, double-blind, HEMORRHOIDS A low-fiber diet is thought to contribute to the etiology of hemorrhoids. 119 Increasing the fiber content in the diet can have a beneficial effect in the treatment of symptomatic hemorrhoids. 120,121 A recent meta-analysis demonstrated that increased fiber reduced the risk of bleeding and decreased the rate of recurrence of hemorrhoids,120 while a Cochrane review found that the risk of not improving hemorrhoids and having persisting symptoms decreased by 53% with increased intake of fiber, with a significant reduction in bleeding. 121CARDIOVASCULAR DISEASE A number of studies have consistently found that a fiber-enriched diet (14 g fiber/1000 kcal energy) is associated with a significant reduction (16 – 33%) in the risk of coronary heart disease (CHD). 19,20,122 – 126 A pooled analysis of studies evaluating dietary fiber Downloaded from imr. sagepub. com by guest on March 27, 2013 10 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiber intake in the USA and Europe indicated that each 10 g/day increase in total fiber intake was associated with a 14% decrease in the risk of coronary events (e. g. myocardial infarction), and a 24% decrease in deaths from CHD. 9 A study on the relationship between dietary fiber and risk of cardiovascular disease (CVD) among women over a 10-year period showed that the ageadjusted relative risk for major CVD was 0. 53 for women consuming the highest amount of fiber (22. 9 g/day) compared with thos e on the lowest fiber intake (11. 5 g/day). 125 Although few interventional studies have specifically assessed fiber intake on the risk of CVD, increased fiber has been shown to ameliorate some of the risk factors for CVD (e. g. high cholesterol levels, high blood pressure, obesity and diabetes). For example, fiber can significantly reduce blood cholesterol levels and so may be important to cardiovascular health. 5,16,81,127 Consuming foods rich in viscous soluble fibers has been shown to reduce blood levels of LDL-C by 10 – 15%, with an expected reduction in CVD events of 10 – 15%, and it has been stated that a diet including 5 – 10 g/day of viscous soluble fiber reduces CVD events and death independent of baseline risk. 18 Although the cholesterol-lowering effect of soluble (especially viscous) fibers probably contributes the most to its cardioprotective effects, other mechanisms are likely to play a role. As part of a lifestyle modification program, fiber can help to reduce blood pressure significantly,128 supporting research that found that highfiber intake was inversely associated with the risk of high blood pressure or hypertension. 129,130 Two intervention trials found that increased fiber intake resulted in significant reductions in blood pressure compared with placebo. 31,132 In an analysis of the association between nutrient intake and risk of stroke, dietary fiber was inversely correlated to the incidence of stroke, a relationship that was stronger in hypertensive than normotensive men. 133 Fiber is also effective at reducing the risk of diabetes and, thus, the risk of developing CVD, and can improve glycemic and insulinemic indices12,14,69 – 71 and decrease blood glucose and insulin levels. 13,16,72 Lowfiber, high-glycemic load diets are associated with higher serum triglyceride levels and lower HDL-C levels, which are risk factors for CVD. 134,135 Increased fiber consumption may also help control body weight and support a weight reduction program by helping to reduce obesity and, possibly, the associated risk of CVD. 94 – 104 Safety aspects of fiber supplementationReduced absorption of trace elements has traditionally been proposed as a potential negative effect of dietary fiber intake;136,137 however, it is unlikely that healthy adults who consume fiber in amounts within the recommended ranges will have problems with nutrient absorption. In fact, clinical data demonstrate that soluble fibers (e. g. inulin, fructo-oligosaccharides, wheat dextrin) may positively affect the absorption of certain minerals. 3,10,11,64,65 Fermentation of dietary fiber by anaerobic bacteria in the large intestine produces gas (including hydrogen, methane and carbon dioxide), which may be related to complaints of distention or flatulence, especially with high intakes of fiber. An increase in dietary fiber should also be accompanied by an increase in fluid intake, and fiber should be increased gradually to allow th e gastrointestinal tract time to adapt.Normal laxation may be achieved with relatively small amounts of dietary Downloaded from imr. sagepub. com by guest on March 27, 2013 11 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiber fiber, and the smallest intake that results in normal laxation should be used. 138 Nevertheless, wheat dextrin has been shown to be well tolerated even up to the relatively high intake of 45 g/day. 51 Higher daily intakes (60 and 80 g) resulted in greater flatulence (P < 0. 05) and some bloating compared with placebo, but no intake resulted in diarrhea. fiber can have beneficial effects on constipation, diarrhea and the symptoms of IBS.Soluble fiber also has additional positive effects on cardiovascular health, leading to a significant risk reduction of CHD. Thus, this review of the physiological effects and subsequent health benefits of soluble fibers suggests that daily fiber supplementation could be beneficial in those individ uals who are at risk of inadequate fiber in their diet. Most servings of common foods contain between 1 and 3 g of dietary fiber so it may be difficult to consume the recommended amounts of fiber. Dietary assessment programs can estimate fiber intake for different population groups, allowing the identification of groups that have deficient fiber intake.At an individual level, fiber intake can be generally estimated based on servings of fruits, vegetables and whole grains having 2 g of dietary fiber per serving, and servings of legumes having 5 g of dietary fiber per serving. Values from high-fiber cereals or fiber supplements can be added to these totals. Wheat dextrin is one example of a soluble fiber supplement that has been shown to help normalize bowel function and is well tolerated, even at large intakes. It is slowly but extensively fermented, leading to a significantly high production of SCFAs, while its slow fermentation profile could help minimize the undesirable effects of gas production and flatulence. Wheat dextrin has also demonstrated enhanced prebiotic capabilities when used at an intake of 30 – 45 g/day.Based on its physiological properties, supplementation with wheat dextrin should be useful in individuals that need to complete their dietary intake with a fiber in order to achieve the daily recommended dietary levels of fiber. Conclusion Review of the evidence indicates that soluble, fermentable fibers, including wheat dextrin, have positive physiological effects that may help to improve bowel regularity and result in some health benefits. Soluble fibers are fermented in the large intestine, leading to the production of SCFAs that lower colonic pH and result in a significant prebiotic effect in which the growth of beneficial intestinal microflora (e. g. ifidobacteria, lactobacilli) and fecal glucosidase concentrations are increased, while the growth of pH-sensitive pathogenic bacteria (e. g. clostridia) is prevented or suppressed. In th is way, SCFAs could promote normal bowel regularity and may help to reduce serum glucose and cholesterol levels. SCFAs also positively influence the absorption and retention of certain micronutrients (e. g. calcium, magnesium, zinc), and may improve immune function by stimulating the production of immunoprotective factors (e. g. T helper cells, antibodies) and improving the barrier properties of the colonic mucosal layer. Soluble fibers that are slowly yet extensively fermented in the large intestine (e. g. heat dextrin) are tolerated more easily than those that ferment quickly, as the latter can produce larger amounts of gas in a shorter period of time, leading to bloating and flatulence. By improving digestive balance, regularity and hydration in the gut, soluble Downloaded from imr. sagepub. com by guest on March 27, 2013 12 JL Slavin, V Savarino, A Paredes-Diaz et al. The health benefits of soluble fiber Acknowledgments Editorial support was given by Deborah Nock, DPP-Cordell Lt d, Saxthorpe, UK. Funding for the review was provided by Novartis Consumer Health, Nyon, Switzerland. Conflicts of interest Alberto Paredes-Diaz and Grigorios Fotopoulos were Novartis Consumer Health, employees at the time of manuscript preparation.The other authors had no conflicts of interest to declare in relation to this article. †¢ Received for publication 8 September 2008 †¢ Accepted subject to revision 9 September 2008 †¢ Revised accepted 11 December 2008 Copyright  © 2009 Field House Publishing LLP References 1 Cummings JH: The effect of dietary fiber on fecal weight and composition. In: CRC Handbook of Dietary Fiber in Human Nutrition (Spiller GA, ed), 2nd edn. Boca Raton: CRC Press, 1993; pp 263 – 349. 2 Kleessen B, Sykura B, Zunft HJ, et al: Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons. 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The health benefits of soluble fiber 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98Increased fecal bile acid excretion and changes in the circulating bile acid pool are involved in the hypocholesterolemic and gallstone-preventive actions of psyllium in hamsters. J Nutr 1999; 129: 896 – 902. Anderson JW, Deakins DA, Bridges SR: Soluble fiber: hypocholesterolemic effects and proposed mechanisms. In: Dietary Fibre – Chemistry, Physiology, and Health Effects (Kritchevsky D, Bonfield C, Anderson JW, eds). New York: Plenum Press, 1990; pp 339 – 363. Juhel C, Tosini F, Steib M, et al: Cholesterollowering effect of non-viscous soluble dietary fiber Nutriose ® FB in hypercholesterolemic hamsters. Ann Nutr Metab 2007; 15(suppl 1): 259.Pratt VC, Tappenden KA, McBurney MI, et al: Short-chain fa tty acid-supplemented total parenteral nutrition improves nonspecific immunity after intestinal resection in rats. JPEN J Parenter Enteral Nutr 1996; 20: 264 – 271. Sanderson IR: Short chain fatty acid regulation of signaling genes expressed by the intestinal epithelium. J Nutr 2004; 134: 2450S – 2454S. Roediger WE: Utilization of nutrients by isolated epithelial cells of rat colon. Gastroenterology 1982; 83: 424 – 429. Koruda MJ, Rolandelli RH, Bliss DZ, et al: Parenteral nutrition supplemented with shortchain fatty acids: effect on the small bowel mucosa in normal rats. Am J Clin Nutr 1990; 51: 685 – 689. Mariadason JM, Barkla DH, Gibson PR: Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model.Am J Physiol 1997; 272: G705 – G712. Blum S, Schiffrin EJ: Intestinal microflora and homeostasis of the mucosal immune response: implications for probiotic bacteria? Curr Issues Intest Microbiol 2003; 4: 53 â €“ 60. Schiffrin EJ, Rochat F, Link-Amster H, et al: Immunomodulation of human blood cells following the ingestion of lactic acid bacteria. J Dairy Sci 1995; 78: 491 – 497. Lissner L, Lindroos AK, Sjostrom L: Swedish obese subjects (SOS): an obesity intervention study with a nutritional perspective. Eur J Clin Nutr 1998; 52: 316 – 322. Kimm S: The role of dietary fiber in the development and treatment of childhood obesity. Pediatr 1995; 96: 1010 – 1014. AlfieriM, Pomerleau J, Grace DM, et al: Fiber intake of normal weight, moderately obese and severely obese subjects. Obes Res 1995; 3: 541 – 547. Nelson LH, Tucker LA: Diet composition related to body fat in a multivariate study of 293 men. J Am Diet Assoc 1996; 96: 771 – 777. Kromhout D, Bloemberg B, Seidell JC, et al: Physical activity and dietary fiber determine population body fat levels: the Seven Countries Study. Int J Obes Relat Metab Disord 2001; 25: 301 – 306. Slavin J, Green H: Dietary fibre and satiety. Nutr Bull 2007; 32: 32 – 42. 99 Jenkins DJ, Wolever TM, Rao AV, et al: Effect on blood lipids of very high intakes of fiber in diets low in saturated fat and cholesterol. N Engl J Med 1993; 329: 21 – 26. 00 Birketvedt GS, Aaseth J, Florholmen JR, et al: Long-term effect of fibre supplement and reduced energy intake on body weight and blood lipids in overweight subjects. Acta Medica (Hradec Kralove) 2000; 43: 129 – 132. 101 Mueller-Cunningham WM, Quintana R, Kasim-Karakas SE: An ad libitum, very low-fat diet results in weight loss and changes in nutrient intakes in postmenopausal women. J Am Diet Assoc 2003; 103: 1600 – 1606. 102 Hays NP, Starling RD, Liu X, et al: Effects of an ad libitum low-fat, high-carbohydrate diet on body weight, body composition, and fat distribution in older men and women. Arch Intern Med 2004; 164: 210 – 217. 103 Howarth NC, Saltzman E, Roberts SB: Dietary fiber and weight regulation. Nutr Rev 20 01; 59: 129 – 139. 04 Pasman WJ, Saris WHM, Wauters MAJ, et al: Effect of one week of fibre supplementation on hunger and satiety ratings and energy intake. Appetite 1997; 29: 77 – 78. 105 Patrick PG, Gohman SM, Marx SC, et al: Effect of supplements of partially hydrolyzed guar gum on the occurrence of constipation and use of laxative agents. J Am Diet Assoc 1998; 98: 912. 106 Schiller LR: Chronic diarrhea. Curr Treat Options Gastroenterol 2005; 8: 259 – 266. 107 Meier R, Burri E, Steuerwald M: The role of nutrition in diarrhea syndromes. Curr Opin Clin Nutr Metab Care 2003; 6: 563 – 567. 108 Alam NH, Meier R, Schneider H, et al: Partially hydrolyzed guar gum-supplemented oral rehydration solution in the treatment of acute diarrhea in children. J Pediatr Gastroenterol Nutr 2000; 31: 503 – 507. 09 Homann HH, Kemen M, Fuessenich C, et al: Reduction in diarrhea incidence by soluble fiber in patients receiving total or supplemental enteral nutrition. 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Thursday, January 9, 2020

Persuasive Argument For Run Nixon Out Of Office - 1245 Words

Barbara Jordan; Persuasive argument to run Nixon out of office On June 17, 1972, G. Gordon Liddy and E. Howard Hunt, members of the Nixon administration, were arrested for the much-publicized scandal of the Watergate burglary. US Representative Barbara Jordan made history on July 28, 1974, with her address on the Articles of Impeachment against then President Richard Nixon and other members of the Nixon house. Jordan explores evidence against the Nixon administration and violations made against the US Constitution by President Richard Nixon, his operatives, and other government officials. She touches briefly of gender and racial equality to convey her connection to the US Constitution, appeals to logic and reason by stating facts†¦show more content†¦In 1956, she graduated from Texas Southern University, then went on to excel in her studies and graduated from Boston University Law School. No other woman had been elected since 1883, til Jordan became the first African American woman elected in the year 1966 to the Texas State Senate. Jor dan’s upbringing plays a significant role in her use of civil religious rhetoric expression in her political speeches. Her highly publicized â€Å"Articles of Impeachment† address to the Judicial Committee is proof of one of her persuasive arguments. Jordan, dressed in a pink blouse, pearl earrings, and spectacles, begins to address the members of the Judicial Committee. She starts her speech by thanking the Chairman for the opportunity of sharing the burden of the impeachment proceedings. She states he is a strong man for handling the responsibility laid out in front of him. She goes on by describing her feelings towards the meaning â€Å"We, the people.† Earlier today, we heard the beginning of the Preamble to the Constitution of the United States: We, the people. It s a very eloquent beginning. But when that document was completed on the seventeenth of September in 1787, I was not included in that We, the people. I felt somehow for many years that George Washington and Alexander Hamilton just left me out by mistake. But through the process of amendment, interpretation, and court decision, I have finally been included in We, theShow MoreRelatedLyndon B. Johnson s President Of The United States Essay1712 Words   |  7 Pagesmembers of congress. One could say that LBJ had an obsessive drive to succeed. This is evident throughout his political career. LBJ met his wife Claudia Alta Taylor, also known as Lady Bird, in 1934. She used her inheritance money to fund LBJ’s 1937 run for Congress. She never stopped serving her husband’s ambitions. Franklin D. Roosevelt was LBJ’s political hero. After meeting with LBJ as a young senator, Roosevelt knew that he was special. President Roosevelt helped LBJ win an appointment in theRead MoreNational Security Outline Essay40741 Words   |  163 Pagessignificance in conflict management development in the contemporary international system. a. Deep division between east and west b. Nuclear weapons have fundamentally altered the war peace dilemma c. The cold war didn’t have traditional wars but hit and run conflicts, proxies CHAPTER 4: The Use of Force in International Relations: Norms Concerning the Initiation of Coercion (JNM) Force may not be used aggressively as an instrument of national policy (as a â€Å"modality of major change or value extension†)Read MoreOrganization Restructuring26680 Words   |  107 Pagesof the organization. (Creech, 1994). Successful organizations like Harley-Davidson, Ford Motor Company, Johnson Johnson, Motorola, Xerox, and others, tell of a long, arduous journey and complete re-organization of their companies from centralized, out-put focused, to de-centralized customer focused before they were capable of reaching their goals of Quality at all levels of the organizations. 6. HOW/WHEN WILL OUTCOMES BE ASSESSED: In order for TQM to be successful, outcomes should be measuredRead MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words   |  1573 Pagesxi Questions for Review 192 Experiential Exercise Biases in Decision Making 193 Ethical Dilemma Do Unethical Decisions Come from Bad Character? 193 Case Incident 1 Computerized Decision Making 194 Case Incident 2 Predictions That Didn’t Quite Pan Out 195 7 Motivation Concepts 201 Defining Motivation 202 Early Theories of Motivation 203 Hierarchy of Needs Theory 203 †¢ Theory X and Theory Y 205 †¢ Two-Factor Theory 205 †¢ McClelland’s Theory of Needs 207 Contemporary Theories of MotivationRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 Pagesbrutally repressive regimes that actively promoted or systematically engineered the massive episodes of rape, oppression, and genocidal killing that were major offshoots of a second global conflict in the early 1940s. The barbarous treatment meted out to tens of millions of men, women, and children in a decade that marked the nadir of recorded human history provided much of the impetus for a worldwide resurgence of human rights activism, agitation, and legislation that came to be centered in the

Wednesday, January 1, 2020

Essay on A Struggle with Fate in Oedipus the King by...

Oedipus the King, a greek tragedy, is the story of a mans struggle against his fate. The author Sophocles, uses many different themes and contrasts in his writing. The most obvious theme being irony. An oracle was given by the priests of Apollo, that a son of King Laius and Queen Jocasta would murder Laius and marry Jocasta. Oedipus was taken as an infant, left to die, but was rescued by a shepard and his wife. Oedipus grows up, not knowing his true identity and fulfills the prophecy. After unknowingly killing King Laius during a chance encounter, Oedipus travels to the city of Thebes, where he solves the great riddle of Sphinx that no one else could solve. The people of Thebes were so overjoyed to be free†¦show more content†¦He assures them, as King, that the murder will be solved and the murderer will be brought to justice. He further calls down the very curses that the people are concerned about upon himself and the nation, saying ...I call down this curse in the gods name: let no crop grow out of the earth for them, their wives bear no children. Rather let them be destroyed by the present plague or something even worse. His final statement, May justice be our ally and all the gods be with us forever!, shows his complete and utter ignorance of th e true identity of the murderer of King Liaus, himself. Oedipus does not realize that he is headed towards destruction by the very words of his mouth. He exhibits a passion to find the murderer and this relentless pursuit will culminate in him being revealed as the murderer. He offers to show mercy to those involved, but ultimately it is he that will need the mercy. The greatest irony is the entire speech itself. Oedipus meant the speech to be honest, upright, and just, but unknown to him every word is the complete opposite. This shows Oedipus, the man desiring to do the right thing, but completely helpless against his fate. Oedipus pursues the murderer relentlessly, and slowly beings to realize the horrible truth of his identity. Queen Jocasta begs him to stop his search, but he vows to keep his promise and find the killer no matter what the cost. He calls in the soul surviving witness to the murder, and he alsoShow MoreRelatedOedipus The King By Sophocles848 Words   |  4 Pages Oedipus the King, written by Sophocles, follows the tragic story of a king named Oedipus who goes from an all-powerful ruler to a hopeless blind peasant. Oedipus the King was written as a play and performed in front of an audience. Sophocles shows in Oedipus the King that one cannot escape the fate of the gods. Throughout the play Oedipus struggles to find a solution and change all the troubles in his life. The play observes the story of Oedipus who defies the gods and through the journey experiencesRead MoreAn Analysis of Fate vs. Free Will in the Theban Plays1392 Words   |  6 PagesAn Analysis of Fate vs. Free Will in the Theban Plays When Teiresias asks in Antigone (line 1051), What prize outweighs the priceless worth of prudence? he strikes (as usual) to the heart of the matter in Sophocles Theban Plays. Sophocles dramatizes the struggle between fate and free will, in one sense, but in another sense the drama might be better understood as the struggle between the will of the goods (which it is prudent to follow, according to Teiresias) and mans will (which is oftenRead More The Iron Hand of Dramatic Irony Essay1571 Words   |  7 PagesThe Iron Hand of Dramatic Irony Sophocles Oedipus Tyrannus is considered by many scholars to be the most significant masterpiece of Greek drama. Through Oedipus Tyrannus, Sophocles is able to develop and establish dramatic irony, a theatrical device that allows the audience to understand the hidden meanings of the words and actions of the characters, though the characters themselves remain oblivious. Therefore, the behavior of the characters become ironic because they are unable toRead MoreThe Role of Faith and the Gods in Oedipus Rex Essays1713 Words   |  7 PagesA common struggle man faces is the question of who or what has power and control over his life. Does he have total control of his future, or is there a higher being at work that takes human lives into their own hands? Sophocles, in his work Oedipus Rex, establishes a view that gives fate, which is created by the gods, a seemingly inescapable characteristic over man. The role of fate is clearly defined, through the fulfillment of divine prop hecy, and Oedipus’ inability to recognize prophecy asRead MoreExposure to Tragedy in Sophocles Oedipus the King702 Words   |  3 PagesSophocles background influenced him to write the drama Oedipus the king. One important influence on the story was his exposer to tragedy all around him. Jeffrey buller in â€Å"Sophocles† told us that Sophocles learned the art form of tragedy from Aeschylus. Sophocles later went to the Great Dionysus a competition for the greatest tragedy and won first place over Aeschylus. Also, Sophocles shows tragedy in the play by telling us about the legend the heard while he grew up (Buller 2-4).Similarly, OedipusRead MoreOedipus The King, Antigone, And Minority Report1364 Words   |  6 Pages Throughout the stories of Oedipus the King, Antigone, and Minority Report, there is a common theme of greatness beyond the scope of the individual story. Oedipus was the dedicated king of Thebes, whose predestined fate detailed failed attempts to outrun his destiny. His sacrifices were for the good of his city. Creon and Antigone battle throughout their story, yet ultimately showed that death and sorrow are fates that are bigger than the both of them. Finally, John Anderton fought to prove his ownRead MoreThe Classical Tragedy Of Sophocles Oedipus The King950 Words   |  4 Pagesâ€Å"Greece’s Golden Age introduced many excellent playwrights, all of whom contributed to the success of Greek Literature† (sites.google/ Playwrights of the Golden Age). Sophocles, the author of the classic tragedy, Oedipus the King, was one of the three best play writers during that time frame. Born in 495 B.C., Sophocles â€Å"lived for nearly ninety years through the most of the turbule nt events of his country during the fifteenth century B.C.† (Charters and Charters). He was born in Colonus, not farRead MoreAnalysis Of Oedipus The King 1696 Words   |  7 Pages HUMN 1110 1 October 2014 Fatalism in Oedipus the King Tragedy has always been considered the highest form of literature; Oedipus the King is written by Sophocles who is one of the three ancient Greek tragedians, it fully represents the enduring charm of the ancient Greek tragedy, leaving the reader endless thinking. Through Oedipus’ misfortune, Sophocles tries to reveal the cause of their tragedy is ubiquitous and ever-present fate, rather than people themselves, dominatesRead MoreOedipus And His Tragic Traits. In Sophocles Play Oedipus1017 Words   |  5 PagesOedipus and His Tragic Traits In Sophocles play Oedipus the King, Sophocles depicts the horrible fate of Oedipus, a pompous, arrogant young ruler. The story begins in the Greek town of Thebes. A plague has descended upon the Thebians causing death and famine throughout the land. Oedipus, being the heroic king, takes full responsibility to find out the cause of their aliments. While working to discover the source of the plague, Oedipus stumbles upon the tragic truth of his heritage and the horrifyingRead MoreSophocles Oedipus The King884 Words   |  4 PagesKing of Thebes, owner of a family tree that identically resembles Medusa on a bad hair day, and the inspiration for a psychologically-riveting complex, Oedipus, tragic hero of Sophocles’ Oedipus the King, exposes troubling truths about the human condition and, acting as an exemplary precaution for the entirety of humanity, demonstrates how a self-destructive struggle between love, anger, and fate, conveyed through an unorthodox love affair between mo ther and son (Who gets custody in a divorce?),